Wilson's disease is a rare genetic disorder characterized by failure to export which metal into bile?

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Multiple Choice

Wilson's disease is a rare genetic disorder characterized by failure to export which metal into bile?

Explanation:
Copper is the metal in question. In Wilson's disease, the liver fails to secrete copper into bile due to a defect in the copper-transporting ATPase (ATP7B). This stops the primary elimination route for copper, so copper accumulates in the liver and then in other organs, causing hepatic and neurologic symptoms. That biliary export defect is the hallmark of the condition, which is why copper is the correct answer. The other metals listed—silver, lead, and aluminum—do not define Wilson's disease and aren’t the characteristic excreted metal in this disorder.

Copper is the metal in question. In Wilson's disease, the liver fails to secrete copper into bile due to a defect in the copper-transporting ATPase (ATP7B). This stops the primary elimination route for copper, so copper accumulates in the liver and then in other organs, causing hepatic and neurologic symptoms. That biliary export defect is the hallmark of the condition, which is why copper is the correct answer. The other metals listed—silver, lead, and aluminum—do not define Wilson's disease and aren’t the characteristic excreted metal in this disorder.

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