True about vesicular transport

• A. I only
• B. I, II, III
• C. II, III, IV
• D. I, IV

Answer: (A)

Vesicular transport is a targeted way cells move materials between compartmental membranes by forming vesicles at a donor site, with coat proteins shaping the vesicle and selecting cargo. After budding, the vesicle is uncoated and carried along cytoskeletal tracks by motor proteins to the correct destination. Docking and fusion are then highly specific: Rab proteins and tethering factors guide the vesicle to the target membrane, and SNARE proteins ensure the vesicle fuses with the right membrane to deliver its cargo. This sequence—coat-mediated budding, motor-driven transport, and SNARE-driven fusion—creates the precise, directional flow of materials inside the cell. Statements that imply diffusion-based movement, non-specific fusion, or transport without the coordinated donor–target system don’t fit how vesicular transport actually works. Hence, the true statement is the one that reflects the essential, coordinated steps of budding with coat proteins and subsequent targeted fusion.