Etanercept is a TNF-α inhibitor used in autoimmune diseases. Which option correctly identifies its target?

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Multiple Choice

Etanercept is a TNF-α inhibitor used in autoimmune diseases. Which option correctly identifies its target?

Explanation:
Etanercept neutralizes TNF-α, a proinflammatory cytokine that drives many autoimmune inflammatory processes. It’s a fusion protein that acts as a decoy receptor, binding TNF-α so it can’t interact with its natural receptors on cells, which reduces inflammatory signaling and tissue damage. That’s why its target is TNF-α. Other options point to different immune mediators or cells (for example, interleukin-1, IL-6 receptor, or CD20) and are targeted by other drugs, not etanercept.

Etanercept neutralizes TNF-α, a proinflammatory cytokine that drives many autoimmune inflammatory processes. It’s a fusion protein that acts as a decoy receptor, binding TNF-α so it can’t interact with its natural receptors on cells, which reduces inflammatory signaling and tissue damage. That’s why its target is TNF-α. Other options point to different immune mediators or cells (for example, interleukin-1, IL-6 receptor, or CD20) and are targeted by other drugs, not etanercept.

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