Advantages of Acetaminophen over Aspirin include the following except

• A. Greater anti-inflammatory action
• B. Less gastric irritation
• C. No appreciable effect on uric acid excretion
• D. No alteration of bleeding time

Answer: (A)

The key idea is comparing what acetaminophen does versus aspirin. Acetaminophen is good for fever and pain but has little to no anti-inflammatory effect, unlike aspirin which reduces inflammation through COX inhibition. That’s why claiming it has greater anti-inflammatory action is not an advantage of acetaminophen; it’s simply not true.

Consider the other points: acetaminophen tends to cause less gastric irritation than aspirin, making it gentler on the stomach. It also does not affect uric acid excretion, whereas aspirin can alter uric acid handling and worsen gout in some patients. Finally, acetaminophen does not change bleeding time, while aspirin prolongs bleeding time due to its platelet-inhibiting effect. So the only statement not representing an advantage of acetaminophen over aspirin is the notion of greater anti-inflammatory action.